Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.3
USERS' SCORE
Good
Based on 17 Reviews
8.3
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%

Top Medical Research Studies

We examined the connection between dietary components and the severity of obstructive sleep apnea (OSA) in a group of 303 adults from Cyprus.

The study indicated that higher energy intake increases OSA severity. However, we noticed that participants with higher folic acid intake tended to have less severe cases of OSA.

Thus, while diet impacts OSA severity, folic acid may offer a protective benefit that could be significant in managing this condition.
Read More
9.5
Weight loss resolves sleep apnea
We examined the effects of bariatric surgery on children aged 8 to 18 facing severe obesity. The study involved 22 children, half of whom had sleep apnea.

Remarkably, children with sleep apnea experienced a significant drop in BMI after surgery, leading to the resolution of their sleep difficulties.

Additionally, many reported improvements in school performance and overall quality of life. While there were a few postoperative complications, the surgeries were deemed safe, promoting the idea that similar interventions can benefit severely obese children.
Read More

Most Useful Reviews

9
Improved sleep quality
21 people found this helpful
After giving birth, I suffered from fatigue and discomfort in my legs, especially at night. Following a recommendation, I began taking this supplement, and almost immediately, my leg pain and sleeplessness improved. My sleep became noticeably better, though I still feel there might be some deficiency.
Read More
9
Improved sleep quality
19 people found this helpful
Taking methylfolate has significantly improved my sleep quality and increased my haemoglobin levels in blood tests. I appreciate this natural form of folic acid as it’s taken once a day, doesn't cause allergies or side effects, and is crucial for pregnancy planning and maintaining beauty. I strongly recommend all women consider periodic courses of methylfolate to address deficiencies and preserve youth.
Read More
9
Addressed sleep apnea
7 people found this helpful
My family has high homocysteine levels, which can lead to sleep apnea and anxiety. After just three days on 5-MTHF, I noticed significant improvements in my sleep. I now sleep through the night.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.3
  • All Researches
9.5
Weight loss resolves sleep apnea
We examined the effects of bariatric surgery on children aged 8 to 18 facing severe obesity. The study involved 22 children, half of whom had sleep apnea.

Remarkably, children with sleep apnea experienced a significant drop in BMI after surgery, leading to the resolution of their sleep difficulties.

Additionally, many reported improvements in school performance and overall quality of life. While there were a few postoperative complications, the surgeries were deemed safe, promoting the idea that similar interventions can benefit severely obese children.
Read More
We examined the connection between dietary components and the severity of obstructive sleep apnea (OSA) in a group of 303 adults from Cyprus.

The study indicated that higher energy intake increases OSA severity. However, we noticed that participants with higher folic acid intake tended to have less severe cases of OSA.

Thus, while diet impacts OSA severity, folic acid may offer a protective benefit that could be significant in managing this condition.
Read More

User Reviews

USERS' SCORE
Good
Based on 17 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved sleep quality
21 people found this helpful
After giving birth, I suffered from fatigue and discomfort in my legs, especially at night. Following a recommendation, I began taking this supplement, and almost immediately, my leg pain and sleeplessness improved. My sleep became noticeably better, though I still feel there might be some deficiency.
Read More
9
Improved sleep quality
19 people found this helpful
Taking methylfolate has significantly improved my sleep quality and increased my haemoglobin levels in blood tests. I appreciate this natural form of folic acid as it’s taken once a day, doesn't cause allergies or side effects, and is crucial for pregnancy planning and maintaining beauty. I strongly recommend all women consider periodic courses of methylfolate to address deficiencies and preserve youth.
Read More
9
Addressed sleep apnea
7 people found this helpful
My family has high homocysteine levels, which can lead to sleep apnea and anxiety. After just three days on 5-MTHF, I noticed significant improvements in my sleep. I now sleep through the night.
Read More
10
Restored sleep hours
1 people found this helpful
After suffering from insomnia for a year due to B9 deficiency, taking methyl folate has been life-changing. I now enjoy 9 hours of sleep daily, a stark contrast to my previous 3-5 hours.
Read More
9
Enhanced sleep patterns
1 people found this helpful
Inositol has greatly improved my sleep quality, allowing me to sleep through the night without waking up. It has truly contributed to achieving long and healthy sleep.
Read More

Frequently Asked Questions

9
Addressed sleep apnea
7 people found this helpful
My family has high homocysteine levels, which can lead to sleep apnea and anxiety. After just three days on 5-MTHF, I noticed significant improvements in my sleep. I now sleep through the night.
10
Restored sleep hours
1 people found this helpful
After suffering from insomnia for a year due to B9 deficiency, taking methyl folate has been life-changing. I now enjoy 9 hours of sleep daily, a stark contrast to my previous 3-5 hours.
7.5
Reduced hormonal issues
7 people found this helpful
After nearly finishing the first package, my well-being has improved significantly; I don’t get hot, and I sleep well at night. I would recommend this product to women experiencing hormonal discomfort. I'm ordering another package.
8
Effective sleep improvement
I began taking methylfolate for two months alongside iron preparations. It has notably improved my deep sleep and increased my haemoglobin levels. I highly recommend it, particularly for its digestibility and synergy with beauty and youth preservation.
6
Eased leg discomfort
4 people found this helpful
The capsules are small and easy to swallow. I have sleep issues related to nerves and blood vessels, and since taking Methylfolate, my restless leg symptoms have disappeared. I hope they do not return once I stop.
9
Improved sleep quality
19 people found this helpful
Taking methylfolate has significantly improved my sleep quality and increased my haemoglobin levels in blood tests. I appreciate this natural form of folic acid as it’s taken once a day, doesn't cause allergies or side effects, and is crucial for pregnancy planning and maintaining beauty. I strongly recommend all women consider periodic courses of methylfolate to address deficiencies and preserve youth.
7.5
Restored sleep routine
15 people found this helpful
For years, I struggled with sleep maintenance issues until I started taking zinc, methyl folic acid, and magnesium. Now, I can sleep for six hours straight, and my overall quality of life has improved significantly.
7
Better sleep
3 people found this helpful
Methylfolate enhances sleep, appetite, and mood while improving metabolism and balancing the nervous system. It is absorbed faster than ordinary folic acid, leading to quicker results. Highly recommended for those who care about their health.
We examined the connection between dietary components and the severity of obstructive sleep apnea (OSA) in a group of 303 adults from Cyprus.

The study indicated that higher energy intake increases OSA severity. However, we noticed that participants with higher folic acid intake tended to have less severe cases of OSA.

Thus, while diet impacts OSA severity, folic acid may offer a protective benefit that could be significant in managing this condition.
9.5
Weight loss resolves sleep apnea
We examined the effects of bariatric surgery on children aged 8 to 18 facing severe obesity. The study involved 22 children, half of whom had sleep apnea.

Remarkably, children with sleep apnea experienced a significant drop in BMI after surgery, leading to the resolution of their sleep difficulties.

Additionally, many reported improvements in school performance and overall quality of life. While there were a few postoperative complications, the surgeries were deemed safe, promoting the idea that similar interventions can benefit severely obese children.

References

  1. Chrysostomou S, Frangopoulos F, Koutras Y, Andreou K, Socratous L, et al. The relation of dietary components with severity of obstructive sleep apnea in Cypriot patients: A randomized, stratified epidemiological study. PLoS One. 2022;17:e0265148. doi:10.1371/journal.pone.0265148
  2. Breaux CW. Obesity Surgery in Children. Obes Surg. 1995;5:279.
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